Menopause: Salivary

Menopause™ is a salivary hormone test for evaluating levels of sex hormones in both women and men. Three specimens — collected over 5 days — are examined for levels of estradiol, estrone, estriol, progesterone, the progesterone/estradiol ratio (P/E2), and testosterone.

To enhance clinical utility, in addition to evaluating patient results against various healthy cohort reference ranges, a therapeutic cohort results cover page is provided for the clinician to quickly and conveniently observe where patient results fall in comparison to a cohort of peri/menopausal women treated with bioidentical hormone therapy.

The Menopause hormone test provides information about the impact that shifting hormone levels can have in women during perimenopause and menopause and in men during andropause (male menopause). The scientific literature confirms that hormone imbalances can be associated with common symptoms such as:

• Hot flashes
• Mood instability
• Anxiety
• Fatigue
• Cognition
• Weight gain
• Low sex drive and performance issues
• Sleep disturbances
• Altered fat metabolism
• Altered blood-sugar control
• Vaginal atrophy
• Hair Loss

Why use the Menopause profile?

Establishing baseline measurements of estrogens, progesterone, and testosterone is critical in determining the need for and response to hormone therapy (HT). The Menopause salivary assessment offers several advantages for patients presenting with hormone-related symptoms:

• Comprehensive testing: three saliva samples, collected every other day over 5 days, provide individual and average levels for estrone (E1), estradiol (E2), estriol (E3), progesterone, the progesterone/estradiol ratio (P/E2), as well as a one-time measurement of testosterone
• Reporting: reference and therapeutic ranges enabling the physician to choose the optimal reference cohort for their patient
• Patient ease-of-use: saliva testing is simple, non-invasive and at-home collection

Imbalanced hormone production affects a wide range of body functions, producing symptoms that negatively affect the quality of life. Identification and targeted treatment of hormonal imbalances using customized hormone and/or nutritional therapies improves symptoms and enhances quality of life.

To meet the individual needs of patients, Genova offers two additional salivary hormone tests in the Menopause series, with varying collection time frames and number of specimens required, depending on clinical objectives.

• Menopause Plus – E1, E2, E3, progesterone, P/E2, and testosterone plus cortisol, DHEA, and melatonin (8 samples; 6 days)
• Menopause Check Plus – E1, E2, E3, progesterone, and testosterone plus post-awakening DHEA (1 sample; 7-9 AM collection)

In addition, a convenient 24-hr snapshot of key hormones is available:

• One Day Hormone Check – E1, E2, E3, progesterone, P/E2, and testosterone plus cortisol, DHEA, and melatonin (5 samples; 24 hr)